Sertraline Oral Liquid and Xanax Oral
Determining the interaction of Sertraline Oral Liquid and Xanax Oral and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Sertraline may increase plasma alprazolam concentrations by inhibiting its CYP450 3A4 metabolism. In healthy subjects, there were no pharmacokinetic changes and there were slight decreases in a driving simulation test score. The clinical significance is believed to be minor.
- Vonmoltke LL, Greenblatt DJ, Cotreaubibbo MM, Harmatz JS, Shader RI "Inhibitors of alprazolam metabolism in vitro: effect of serotonin-reuptake-inhibitor antidepressants, ketoconazole and quinidine." Br J Clin Pharmacol 38 (1994): 23-31
- Hassan PC, Sproule BA, Naranjo CA, Herrmann N "Dose-response evaluation of the interaction between sertraline and alprazolam in vivo." J Clin Psychopharmacol 20 (2000): 150-8
- Gilman AG, Rall TW, Nies AS, Taylor P, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 8th ed." New York, NY: Pergamon Press Inc. (1990):
Generic Name: sertraline
Brand name: Zoloft
Synonyms: Sertraline
Generic Name: alprazolam
Brand name: Niravam, Xanax, Xanax XR, Alprazolam Intensol
Synonyms: Xanax
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Sertraline Oral Liquid-Xanax XR
- Sertraline Oral Liquid-Xanax XR Oral
- Sertraline Oral Liquid-XaQuil XR
- Sertraline Oral Liquid-Xarelto
- Sertraline Oral Liquid-Xarelto Starter Pack
- Sertraline Oral Liquid-Xartemis XR
- Xanax Oral-Sertraline Oral Solution
- Xanax Oral-Sertraline Tablets
- Xanax Oral-Servira
- Xanax Oral-Serzone
- Xanax Oral-Setlakin
- Xanax Oral-SetonET