About us Contacts Drug interactions: 390 212
Drug search by name

Tandem and Zinc Gluconate Capsules and Tablets

Determining the interaction of Tandem and Zinc Gluconate Capsules and Tablets and the possibility of their joint administration.

Check result:
Tandem <> Zinc Gluconate Capsules and Tablets
Relevance: 24.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Iron and zinc may reduce each other's absorption when they are coadministered orally. The mechanism of interaction is unknown. In clinical studies, concurrent supplementation with iron and zinc was associated with reduced efficacy in improving the growth and iron and zinc status of malnourished infants compared to supplementation with either one alone. It is not known whether the interaction occurs in adults. In any case, the clinical significance is probably minimal in healthy individuals. However, monitoring for reduced therapeutic response may be advisable in malnourished patients. Limited data suggest that the magnitude of the interaction may be lessened by separating the times of administration of each by 12 hours.

References
  • Lind T, Lonnerdal B, Stenlund H, et al. "A community-based randomized controlled trial of iron and zinc supplementation in Indonesian infants: interactions between iron and zinc." Am J Clin Nutr 77 (2003): 883-90
  • Sreedhar B "Conflicting evidence of iron and zinc interactions in humans: does iron affect zinc absorption?" Am J Clin Nutr 78 (2003): 1226; author reply 1226-7
Tandem

Generic Name: ferrous fumarate / iron polysaccharide

Brand name: Tandem

Synonyms: n.a.

Zinc Gluconate Capsules and Tablets

Generic Name: zinc gluconate

Brand name: Orazinc, Orazinc 110

Synonyms: Zinc gluconate, Zinc Gluconate

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle